NAD⁺ is a coenzyme that occurs in two closely linked forms: as NAD⁺ and as NADH. Both forms are part of a system that is essential for energy production in the cells. Put simply, NAD⁺ helps to convert nutrients into energy, which the body needs for movement, thinking and regeneration.

This process takes place primarily in the so-called mitochondria, the “powerhouses” of the cells. This is where ATP is formed, the body's most important energy carrier. If not enough NAD⁺ is available, this process may work less efficiently. This can become noticeable, for example, through tiredness, reduced performance or slower recovery.

In addition to energy production, NAD⁺ is also involved in other important tasks. It supports enzymes that are responsible for repairing cell damage and plays a role in the cells' adaptation to stress. Because of these varied functions, NAD⁺ is regarded as a central building block for stable cell function and a good capacity for regeneration.

For the body, NAD⁺ is something like a “key helper” at the cellular level. Without NAD⁺, many processes that provide energy and keep cells stable run considerably less efficiently. NAD⁺ is particularly important where the body turns food and oxygen into usable energy, namely in the mitochondria. Here, NAD⁺ ensures that biochemical reactions run smoothly and that enough ATP is ultimately produced – that is, the energy carrier every cell needs for its daily work.

In addition to energy supply, NAD⁺ also plays a role in how well cells cope with stress. It is involved in systems that control repair and protective functions, for example in the maintenance of DNA and in cellular adaptation mechanisms. Put simply, NAD⁺ thus supports not only performance but also regeneration and resilience.

NAD⁺ also influences the so-called redox balance, that is, the balance between oxidative processes and the protective mechanisms against oxidative stress. This balance is important because oxidative stress can place a strain on cells in the long term, particularly when inflammation, lack of sleep or persistent stress are added.

The NAD⁺ level is not fixed. It changes over the course of life and is partly determined by lifestyle and stresses. With increasing age, the body's own production declines. At the same time, consumption often rises, for example with chronic stress, inflammatory processes, high UV exposure, lack of sleep or certain illnesses. The body can produce NAD⁺ itself, among other things from vitamin B3 and from metabolic products of tryptophan, but this endogenous production is not always sufficient when the requirement rises.

When less NAD⁺ is available, many people report changes that come on gradually rather than suddenly: less drive, lower resilience, slower recovery.

In an NAD⁺ infusion, the coenzyme is administered directly via the vein. In this way, it enters the bloodstream immediately and does not first have to be absorbed via the gastrointestinal tract. This can be particularly useful when rapid and reliable availability is the aim.

A session generally lasts between 90 and 120 minutes. Lecturer Dr. Matiasek adjusts the dosage and the rate of the infusion individually. Many people find the treatment calm and not very taxing and can usually continue their daily routine afterwards without any problems.

Intravenous administration allows the NAD⁺ level in the blood to be raised in the short term. How strongly and for how long this increase affects the cells can vary from person to person. In practice, the main focus is therefore on whether energy, drive or resilience in everyday life noticeably improve.

The aim of the NAD⁺ infusion is to increase the availability of this important coenzyme in the short term. In practice, many people report a noticeable increase in energy and drive. Lecturer Dr. Matiasek uses the infusion in particular when patients feel exhausted or would like to stabilise their physical and mental performance again.

In addition to energy, a better ability to concentrate is also frequently described. As nerve cells have a particularly high energy requirement, an improved supply may play a role here. Some people find their mental clarity more stable and feel more focused in everyday life.

Furthermore, supporting cellular repair processes can help the body to recover better overall.

Before an NAD⁺ infusion, a medical consultation takes place with Lecturer Dr. Matiasek, in which your medical history, current stresses and individual goals are discussed. Pre-existing conditions, medication and possible contraindications must be taken into account.

Where appropriate, preliminary examinations may be useful in order to assess the treatment medically. On this basis, a decision is made as to whether an NAD⁺ infusion makes sense at all in the individual case and at what dosage it should be given.

The infusion is given intravenously via a venous access and generally takes 90 to 120 minutes. Slow administration is important, as giving it too quickly can be associated with side effects.

During the infusion, patients are medically monitored. Lecturer Dr. Matiasek adjusts the dosage and infusion rate to your needs.

After the treatment, most people are able to go about their daily routine. Nevertheless, it is advisable to avoid physical exertion on the day of the infusion and to ensure adequate fluid intake.

Mild side effects such as tiredness, headaches or a temporary feeling of being unwell may occur and generally subside quickly. If symptoms persist, please do not hesitate to contact Lecturer Dr. Matiasek.

The possible side effects of an NAD⁺ infusion include nausea, dizziness, headaches, fluctuations in blood pressure or vein irritation. In rare cases, circulatory reactions may occur, particularly if the infusion is given too quickly.

For this reason, the treatment should only be carried out under medical supervision.

There is no general answer to this, and it depends on your individual response. Lecturer Dr. Matiasek will be happy to advise you on dosage and frequency in a personal consultation.

How quickly does an effect set in and how long does it last?

Subjective effects are frequently described within one to two days and, according to reports from those treated, last for several weeks.

An NAD⁺ infusion could be suitable for you if you notice that your energy in everyday life is no longer as stable as it used to be. Many patients report that, despite sufficient sleep, they feel exhausted more quickly, find it harder to start the day or need longer to recover after exertion.

An NAD⁺ infusion can also be useful in cases of high mental or physical demand. When work-related stress, long working hours or intensive training phases persist over a longer period, the body's own reserves sometimes become unbalanced. In such situations, NAD⁺ is used to give better support to energy, drive and resilience once again.

In addition, the infusion may be of interest to you if you would like to stabilise your concentration and mental performance. As the brain has a particularly high energy requirement, some people report more clarity and focus, especially in phases of increased mental demands.

Many people also opt for an NAD⁺ infusion as part of a preventive longevity approach, in order to strengthen metabolism and regeneration at an early stage. This is less about acute complaints than about the aim of remaining capable and productive in the long term.

Before every treatment, Lecturer Dr. Matiasek discusses with you whether an NAD⁺ infusion makes sense in your individual situation. It is important that the infusion does not replace fundamental factors such as sleep, nutrition, exercise and stress management, but specifically complements them.

The advantage of an infusion lies above all in the fact that NAD⁺ is administered directly via the vein and is therefore quickly available. Many people experience this as a noticeable effect on energy and drive. In practice, it is frequently reported that resilience in everyday life improves and that people feel mentally more alert or clearer, particularly in phases of high demand.

In addition, NAD⁺ is used because it is involved in cellular processes associated with regeneration and repair. If you have the impression that your body is regenerating more slowly, you could benefit from an NAD+ infusion. The ability to concentrate is also frequently described as more stable, which fits well with the fact that nerve cells in particular have a very high energy requirement.

As the infusion bypasses the gastrointestinal tract, it is also of interest to people who tolerate oral preparations poorly or for whom a direct, easily controllable supply is preferred.

If you are interested in an NAD⁺ infusion and would like to find out whether this treatment makes sense for you, you are welcome to arrange an appointment with Lecturer Dr. Matiasek for a personal discussion.